ORDER

AND NOW, this 17th day of May 2011, the Petition for Allowance of Appeal is GRANTED. The issues, as stated by petitioner, are:

(1) Whether application of 77 P.S. § 411(2), the “disease manifestation” provision of the Pennsylvania Workers’ Compensation Act (“Act”), in concert with 77 P.S. § 481, the “exclusive remedy” provision of the Act, results in an unconstitutional denial of the “reasonable compensation” mandate of Article III Section 18 of the Pennsylvania Constitution, which underlies the historical quid pro quo worker’s compensation bargain, for a latent occupa *406 tional disease that is invariably non-compensable under the Act?

(2) Whether it is a violation of the Open Courts and Remedies Clause of Article I Section II of the Pennsylvania Constitution and the Due Process and Equal Protection Clauses of the federal and state constitutions to foreclose a common-law remedy in exchange for providing a wholly emancipated “substitute remedy” in contravention of the “reasonable compensation” mandate of Article III Section 18 for an occupational disease which is invariably non-compensable under the Act?

(3) Whether the plain language of 77 P.S. § 411(2) defines an “injury” under the Act such that it excludes from its definition an occupational disease that first manifests more than 300 weeks after the last occupational exposure to the hazards of such disease, so that the exclusivity provision of 77 P.S. § 481 is not invoked?