Defendant-Appellant George James Jr. appeals his 172-month sentence imposed after he pled guilty to possession with intent to distribute five grams or more of cocaine base, in violation of 21 U.S.C. § 841(a)(1). No reversible error has been shown; we affirm.

Defendant faced a statutory minimum sentence of five years and a maximum term of forty years. The PSI concluded that Defendant — a career offender — was subject to a guideline range of 188 to 235 months. Defendant requested (i) credit for time spent in state custody for an unrelated conviction, (ii) a sentence con *936 current with a state sentence, (iii) a downward departure based on diminished mental capacity, and (iv) a downward variance based on his mental illnesses and difficult upbringing. The district court accommodated the first two requests: the sentence imposed runs concurrently with a state sentence and is 16 months below the guideline range (to correct a delay between Defendant’s federal indictment and the commencement of federal custody). No further downward departure or variance was granted. Defendant raises a single sentencing issue on appeal: whether the sentence imposed was unreasonable under the section 3553(a) factors, 18 U.S.C. § 3553(a), in the light of Defendant’s diminished mental capacity and difficult childhood. *

Appellate review of the substantive reasonableness of a sentence — whether inside or outside the guidelines range — is under an abuse-of-discretion standard. Gall v. United States, — U.S. -, 128 S.Ct. 586, 597, 169 L.Ed.2d 445 (2007). This review is deferential; and “the party who challenges the sentence bears the burden of establishing that the sentence is unreasonable in the light of both [the] record and the factors in section 3553(a).” United States v. Talley, 431 F.3d 784, 788 (11th Cir. 2005). And even if an appellate court disagrees with the weight the district court afforded the section 3553(a) factors, we will reverse only if the final sentence imposed lies outside the range of reasonable sentences. See United States v. McBride, 511 F.3d 1293, 1297-98 (11th Cir. 2007).

The transcript of the sentencing hearing makes it clear that the district court considered the section 3553(a) factors; and the district court noted specifically Defendant’s (i) mental capacity and the psyehological reports submitted on his behalf, (ii) family situation, (iii) difficult childhood, and (iv) positive influence of Defendant’s new girlfriend. But the district court was unpersuaded that these factors justified a variance from the advisory guideline range. We cannot say the 172-month sentence imposed — well below the statutory maximum of 480 months and 16 months below the low end of the guideline range— was “outside the range of reasonable sentences dictated by the facts of the case.” United States v. Williams, 456 F.3d 1353, 1363 (11th Cir. 2006), cert. dismisse d — U.S.-, 127 S.Ct. 3040, 168 L.Ed.2d 755 (2007), abrogated on other grounds Kimbrough v. United States, — U.S. -, 128 S.Ct. 558, 169 L.Ed.2d 481 (2007). No clear error of judgment in weighing the section 3553(a) factors has been shown.

AFFIRMED.