Erika Jean Riker pled guilty to possession of fifty grams or more of cocaine base (crack) with intent to distribute, 21 U.S.C.' § 841 (2000), and was sentenced to a term of 121 months imprisonment. Under the terms of her plea agreement, Riker waived the right to appeal her sentence. She now seeks to appeal the district court’s determination at sentencing that she was not entitled to an adjustment for acceptance of responsibility, U.S. Sentencing Guidelines Manual § 3E1.1 (2002), and did not qualify for a reduction under the safety valve provision, USSG § 2Dl.l(b)(6). For the reasons explained below, we dismiss the appeal.

A defendant may waive the right to appeal if that waiver is knowing and voluntary. United States v. Brown, 232 F.3d 399, 402-03 (4th Cir. 2000); United States v. Broughton-Jones, 71 F.3d 1143, 1146 (4th Cir. 1995). To determine whether a waiver is knowing and voluntary, this Court examines the background, experience, and conduct of the defendant, as well as the defendant’s familiarity with the plea agreement. United States v. General, 278 F.3d 389, 400 (4th Cir. 2002) (internal citation omitted). If the district court fully questions a defendant regarding the waiver of his right to appeal during the Fed. R.Crim.P. 11 colloquy, the waiver is usually both valid and enforceable. United States v. Wessells, 936 F.2d 165, 167-68 (4th Cir. 1991); United States v. Wiqqins, 905 F.2d 51, 53-54 (4th Cir. 1990). The transcript of Riker’s guilty plea hearing reveals that the district court adequately questioned Riker about her understanding of the waiver provision and that her waiver was knowingly and intelligently made.

We therefore dismiss the appeal. We dispense with oral argument because the facts and legal contentions are adequately presented in the materials before the court *941 and argument would not aid the decisional process.

DISMISSED